Originally posted by Mringasa:

I use them on Serpents a lot. Poison them, harpoon them and drag to a beach. Draugr Fang is of course better for this, but poison arrows + finewood or huntsman bow is a decent alternative.

Terrible choice. Serpents are resistant to poison. You should use Frost Arrows on them as they are always Wet due to being in water which makes them weak to frost damage.