Yeah, tip # 1 for tamed wolves: Don't bring them to the swamp, unless you've bred a sizable pack, and don't mind losing a lot of them along the way.

Even 2* wolves have a difficult time in the swamp, they're very susceptible to poison.

Tip #2: Don't bring your lone tamed wolf *anywhere*. Keep it in a well-defended pen at your base, tame a second one, and keep at least a base pair to use as breeding stock.