Originally posted by Mitrovarr:

It wouldn't really change much, to be honest. The odds your starting biomes would have boss spawners is pretty low. So realistically it wouldn't affect anything until you actually went looking for the bosses and found the nearest spawn location, in which case you'd have to hunt them down but wouldn't have to spawn them manually.

The only really serious effect would be with Eikthyr, which you would probably encounter extremely early, way before you could deal with it.

Fair point, maybe have bosses like bonemass appear in swamps that contain crypts only. That way no iron without being on his territory.

I can see Eikthyr destroying beginner bases. Maybe he would need a script where you can see him in the distance from time to time. For others you'd have to scout the surrounding before deciding if you wanna settle in the biome.

Someone pointed out that Elder's roots hit wherever you are, so there could be like roots attacking you from time to time when you're in his forest until you find him.

Didn't deal with Moder or the one after yet so IDK how it would go.