I set myself "rules" every playthrough. !00 Days before/between killing each boss so that I spend time exploring my maps, building a very suitable locations and stockpiling resources at a leisurely pace. During these play-throughs I give myself a 3 Life limit. 3 Deaths and I start over. I've had tonnes of fun, discovered some gorgeous seeds with great quality of life; ie can walk to the Merchant from starting area with little difficulty, and some where the second boss was a grueling trip.