seeds vary dramatically.
you could have to sail in one just to get copper, or iron, and in another have it be a short walk.
you can get stupidly lucky getting a build site or easy time of finding iron and trader, or those can take days of searching.
but after a few goes, for sure, its the same old same old. At that point, its really a question of whether you enjoy making new homes and exploring the world just to see it and poke around, or if you are bored with no more progression or nothing new to do/discover.
I like to build, and farming materials to feed that keeps one pretty busy.