I tend to build a new base in a friendly biome (I consider Black Forest "friendly") close to where I'm going to harvest/mine ore and just process it on the spot.

Mountains differ a bit from that, in that I build a base at the foot of the mountain. On the top of the mountain where the silver nodes are, I place a portal and a chest. I then proceed to mine as much silver as possible and put it in the chest. Then I take as much as I can carry and run down the mountain to my base, and jump through the portal to be back up where the chest with the goodies is. Rinse, repeat.

But then I like building and I also don't mind a lot of things that others see as "tedious", so YMMV.