I start over whenever I feel like it. I enjoy the early game, where you have to get established and just taking on some boar could get you killed if you're not paying attention. I started over again for mistlands, I figure that way by the time I get to mistlands the balance and bugs should be settled. I'm about ready to start mining frost caves before I go kill moder and move on the plains.

I've yet to have a world where I'm so happy with my progress and camps that I take on the harder unnecessary challenges: tame 2 star wolves, harpoon serpents and drag them home to legitimately get trophies & scales without floating items mod, etc.

Mind you I'm an introvert hermit, having my own little world to run around is all I ever wanted in life. That I can just generate a new one whenever.. awesome.