ya poison resist and good food is a must for swamp. i try to find another biome besides plains hopefully meadows to build a small base at, or an island of black forest off the coast or stone tower is good portal shelter. if its all swamp do a drive by where u make land with your fine wood bow and look for a easy crypt 2 run 2, put down a workbench at the crypt jump on it and onto the crypt and make a portal to your base so u can repair ur pick axe, and u dont lose track of the crypt u are in, mark crypts as done or not done on the map as u scout them out, i like driving my boat into the swamp if i can, backwards so if it gets destroyed i can reach the materials, make sure to mark ur boat as well rofl ive had trouble with that.