Porcupine is an awesome general purpose weapon. You also really should carry a bow. Draugr Fang is the current King of Bows but the Huntsman's Bow is pretty good too and it's quiet. After that, it's dealer's choice!
Recently I've been running with the Blackmetal Atgier. I've found it to be solid and I think it's the best weapon to use when hunting Lox. The Blackmetal Sword won't let you down.
For fun, everyone should try the Flesh Rippers. They are hilarious in the Meadows and Black Forests. Punting a Greydwarf off the side of a cliff never gets old, plus they don't slow you down when active. It's good to try and have a mix of damage types in your hot bar. Eight slots gives you access to most everything you need quickly: Shield, Sword, Atgier, Bow, Hammer, Axe, Pickax, and Hoe is how I have mine. The third slot I'll swap out for different things like a Porcupine or the Flesh Rippers depending on how I want to run.