Biome intersetcions are (allmost) dangerous to build but can be funb at the same time
often you can watch the creatures fighting themselves

if you are up to build near a biome with stronger (stronger than you) enemys allways be prepared to get in contact with them

your better of getting fully equipped with the best available armor, weapons and food, and then build a new base at the border of a biome.

otherwise i recomend taking over a small hut somewhere nearby and use it as a base of operation for future buildings