Originally posted by jonnin:

I can imagine that with a bag full of spare bows and fire arrows you could clear a mine. Getting 5 cores RNG factor may doom the attempt but it seems possible. Seems like more work than its worth, but possible. Getting into the mine alone, with the entry guarded, is going to be a pretty epic dodge and run. Could be a case for a tower shield?

You can get ice and poison arrows very early in the game by just harvesting some obsidian with Frost protection potions. Those arrows deal a lot of damage to Seekers.