Originally posted by Grailoch:

For me it is the same issue I have with portals, food. Farms are not easily relocated (or, do I really want to set up a farm here for the short time I will be getting materials here?). Boars for sausage are either in Meadows or a boar farm I have set up, both possibly a long way away from my current material farming location. The difference is, with portals I can get back to Meadows/Farm/Etc very quick to restock food items (and later meads). Not so much without them.

I haven't tried playing with no portals yet, but I'm thinking about trying it. If I did try it, I would look for base locations that are within reach of all, or at least many of the biomes. In my experience, that's not hard to find, and where I tend to place my main bases anyways.

I have one large base that sits on the intersection of meadows, black forest, and plains. Swamp is just a 30 second walk away, and mountain is maybe a couple of minutes.