I use game pad because I play Xbox some also. I am left-handed and have always had mouse on the left side of of the keyboard. The key setup is for the left hand to be on the keyboard, the right hand on the keyboard just does not work for me. I tried to change the keys to have the setup pattern like that of the left hand but run into the comma, bracket keys that won't select in the key change. Still have to use keyboard to split items in inventory, but that not bad.