I have found rolling helps a lot when facing multiple seekers, as its 1 stamina drain for an i-frame rather than blocking multiple attacks.

And I would agree Mistlands feels like it needs some balance tweaks, with nearly all the gear upgrades locked at the very end of the Biome's resource progression , upgrades currently capped at level 2, and the armor/damage of the new gear being extremely marginal increases from the best of the Plains tier equipment.