Originally posted by Latcady:

Just bare in mind that building in a biome on your map that is not currently populated like Mistlands could backfire when that biome gets updated in future because the update may not be able to apply on that map. So you may end up having to start a new game in that instance, which may be frustrating if you put a ton of work into building etc.

So, if you want to keep a chance of a map being playable through the future updates, it's a good idea to avoid uncovering & building in Mistlands etc.

**No one is 100% sure whether this will totally protect you from having to start a new map when a future content update is released, I do know the devs approach is to try and avoid that kind of forced restarting if possible, but better safe than sorry if you can avoid it now!

Also I literally built a castle for my inert pick up storage. I am a hoarder, I need help.

i haven't been playing lately but most people seem to speculate that we will need to roll a new map/seed in order to enjoy the full spectrum of new patch content. Also, setting up a shack with a portal and bed takes like 5 seconds and virtually no materials. This will be much easier for most players when just entering the plains than trying to settle in the plains itself.