Originally posted by McCloud:

Can I put a few hundred work benches in a swamp, every 30-40 yards apart, and stop all the "normal" spawns there?

I just don't want to deal with that place.

A bit excessive but one way I avoided most issues in the swamp was using campfires(yes even if burned out) along paths in the terrain that used the hoe to raise the ground on. I also placed covered benches on top of all crypts and I made sure to break all spawners. So while it didn't kill spawns of all things, it minimized them and made travel in the swamp more amiable.

You dont want all mobs to completely stop spawning though as they are a harvestable resource. You just want to be able to manage them better is all.