My last permadeath run was incredible, sharing what was most important to me:

1. Weaknesses matter far more than your skills:
- Blunt damage for Skeletons
- Pierce damage for Trolls
- Slash damage for Tree creatures (Elder too)

2. Stamina is a deeper mechanic than most people think it is, blocking lowers your stamina regen, heavier armor takes more stamina away when you dodge, and efficient blocking can save a lot on stamina compared to parrying. However, you rarely ever need Stamina food in combat. Take it from me, eat lots of meat and you will never die.

3. Potions are underrated. Stack up on health potions!

4. Max your comfort out asap as well, always stay rested no matter what. Not being able to run from a fight is a slow painful death sentence.

5. And of course.. DODGE!